Intra Ventricular Colistin in Neonatal Brain Abscess Management: A Case of Multiple Brain Abscesses

نویسندگان

چکیده

Neonatal Brain abscess is a rare sever neonatal infection requiring careful medical and neurosurgical intervention strategies to reduce morbidity mortality rates. Gram-negative bacterial agents are the most common pathogens involved in brain abscesses of neonates. The use wide spectrum antibiotics combination with drainage larger than 2.5 cm mainstay treatment. Colistin polymyxin antibiotic used treat infections caused by susceptible gram-negative bacteria but limited penetration blood barrier. However, there data on using intraventricular intracranial infections. A 12-day-old male neonate multiple frontal parietal lobes presented. were successfully managed intravenous antimicrobial agents, concurrent administration Interferon-ɣ. Subsequently, he developed ventriculomegaly which was endoscopic third ventriculostomy. He had an acceptable neurologic outcome. Due reduced colistin barrier, its form can be beneficial management abscesses. Concurrent Interferon-ɣ may improve treatment process outcome given that secretion this agent T lymphocytes contribute partial immunodeficiency state at period life.

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ژورنال

عنوان ژورنال: American journal of pediatrics

سال: 2022

ISSN: ['2472-0909', '2472-0887']

DOI: https://doi.org/10.11648/j.ajp.20220801.14